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Neurology Conference
Hall 1

Keynote Presentation

Title : Neural Population Computing Part 2. Emotions
Dr. Stephen E. Nadeau, University of Florida College of Medicine, USA

Dr. Nadeau studied chemical physics and political science at the Massachusetts Institute of Technology and achieved a medical degree at the University of Florida College of Medicine. After one year of post-MD fellowship training with Kenneth M. Heilman, he has devoted his research career mainly to cognitive neurology and, in particular, to understanding how higher neural functions can be supported by actual neurons. He is currently Professor of Neurology at the University of Florida. He has published two books and 158 peer-reviewed publications and book chapters.

Abstract:

Neurology Conference 2025
Hall 1

Keynote Presentation

Title : Plasma Biomarkers in Alzheimer’s Disease and COVID-19 Subjects
Dr. Allal Boutajangout, NYU Langone Health, USA

My current research focuses on Alzheimer’s disease and related disorders, with a particular interest in immunotherapy. I am currently in the process of testing the efficacy of generated antibodies in different neurodegenerative diseases, in addition to identifying novel blood biomarkers for the prediction and monitoring of disease progression- crucial for detection of early stage AD.

Neurology Conference 2024
Hall 1

Keynote Presentation

Title : Is ALS onset accelerated by chloroviruses and delayed by antiviral immune responses?
Dr. Gary L Pattee, Bryan Physicians Network, USA

Dr. Gary L. Pattee is a neurologist in Lincoln, Nebraska and is affiliated with multiple hospitals in the area, including Nebraska Medicine-Nebraska Medical Center and Bryan Medical Center. He received his medical degree from McGovern Medical School at UTHealth and has been in practice for more than 20 years. They treat headaches, stroke, dementia, seizures, epilepsy, multiple sclerosis, sleep disorders and neuromuscular diseases.

Asli Beyza GUL
Hall 1

Young Researcher Presentation

Title : Advancing Parkinson’s Care: Integrative Technology Solutions for Enhanced Patient Management
Asli Beyza Gul, Aston University, Birmingham, UK

Asli Beyza Gul is a dedicated medical student at Aston University, Birmingham, UK. She is deeply committed to advancing neurology with a focus on geriatrics. Conducting internationally recognized research on Parkinson’s patient management during the pandemic, Asli showcases her dedication to making a difference in this field. As the founding president of Aston Neurology Society, she demonstrates exceptional leadership and a passion for making a difference. Asli’s drive and passion position her as a promising future leader in the field, poised to enhance the lives of patients and contribute significantly to medical research and practice.

Neurology Conference 2024
Hall 1

Keynote Presentation

Title : Positive Assertiveness and Integrative Meta Learning Approach could facilitate improved rehabilitation outcome and maximised independence for people with severe spinal cord injury that led to permanent disability.
Dr. Merima Isakovic– Inspire Mindful Psychology, Australia

Dr Merima Isakovic is the founder and Director of the Inspire Clinical Psychology practice. She is Inspire’s Principal Clinical Psychologist and the Clinical NeuroPsychologist. She has devoted her working life to building a safe and nurturing nest where all Psychologists in her Inspire practice are genuinely warm, respectful and empathic practitioners with high ethical values. Dr Merima is exceptionally warm, devoted and skilled at helping people, with many years of professional experience in psychotherapy, neuropsychotherapy, psychological counselling, clinical & neuropsychological assessment, as well as  research, clinical supervision and mentoring across Australia and internationally. Dr Merima is a well-respected member of the Australian Psychological Society (APS) as well as New Zealand Psychological Society  (NZPS) and highly regarded Clinical Supervisor among the Colleague Psychologists.

NEUROLOGY CONFERENCE 2024
Hall 1

Kynote Presentation

Title : Exploring Psychopathology with Brain Fingerprinting Technique (Bft): A Paradigm Shift in Psychiatry
Dr. Anand Pratap Singh – Gautam Buddha University, India

Dr Anand Pratap Singh is currently working as Head, Department of Psychology & Mental Health, at Gautam Buddha University, India  since July, 2012.  Before joining the GBU, he has served at KGMU, Lucknow, Amity University, Noida, and Apollo Hospital Delhi in various capacities.  His area of expertise has been Brain fingerprinting, Neuro-Cognition and Neurofeedback Therapy. Till the date, he has supervised 08 Ph. D. theses and 29 M. Phil theses in the area of Clinical Neuro Psychology. He has published 40 research papers and book chapters to his credit in reputed National & International Journals & books. He is the Chief Editor of India Journal of Behaviour Research & Therapy (IJBRT) and Editor of SIS journal of Projective Psychology.

Hall 1

Oral Presentation

Title :   Time is Brain: A preoperative Neurological evaluation before Surgery
Dr. Giuseppe Bonavina- Neurointensive Care Unit, Montecatone Rehabilitation Institute, Imola, Bologna, Italy

Dr. Giuseppe Bonavina, a distinguished Consultant Neurologist, hailing from Bologna, Italy, has made significant contributions to the field of neurology. His journey began with research at the University of Bologna, where he delved into headaches, cranio-facial pain, and the autonomic nervous system from 1999 to 2003. Today, Dr. Bonavina serves as a Neurologist in the Neurointensive Care Unit at Montecatone Rehabilitation Institute in Imola, Italy.

Neurology Conference
Hall 1

Keynote Presentation

Title : Repair and Remodeling of Cerebral Nerve in Children with Cerebral Palsy by Acupuncture
Dr. Zhenhuan LIU, Professor of Pediatric Neurologist in Nanhai Affiliated Hospital for Women and Children Guangzhou University Chinese Medicine Guangdong CHINA

Zhenhuan Liu professor of pediatrics,Pediatric acupuncturist Ph.D.tutor. He has been engaged in pediatric clinical and child rehabilitation for 40 years. Led the rehabilitation team to treat more than 40,000 cases of children with intellectual disability, cerebral palsy and autism from China and more than 20 countries,More than 26800 childrens deformity returned to school and society and became self-sufficient. The rehabilitation effect ranks the international advanced level.Vice-chairman of Rehabilitation professional committe children with cerebral palsy,World Federation of Chinese Medicine Societies. Visiting Profassor of Chinese University of Hong Kong in recent 10 years. .He is most famous pediatric neurological and rehabilitation specialists in integrated traditional Chinese and Western medicine in China. He has edited 10 books.He has published 268 papers in international and Chinese medical journals.

neurology conference 2023
Hall 1

Keynote Presentation

Title : Neurostimulation and Neurofeedback modalities designed to restore functionality to the Brain.
Nicholas J. Dogris, CEO of NeuroFiled.INC

Dr. Dogris is the CEO and Co-founder of Neurofield, Inc., a company that develops specialized neurostimulation and neurofeedback modalities designed to restore functionality to the brain. He is a licensed psychologist in the state of California and specializes in Health Psychology, wellness and mind body physiology. He is an expert in QEEG brain mapping and is a board certified QEEG Diplomate. He is also board certified in neurofeedback through the Biofeedback Certification International Alliance (BCIA). Over the last 25 years Dr. Dogris has innovated many neurofeedback interventions and invented the NeuroField neurostimulation/neuromodulation system in 2007. In clinic, he continues to innovate and create new ways to bring balance to the brain in the effort to improve the functionality of the person.

Hall 1

Keynote Speaker Presentation

Title :  A Noninvasive Neuroimaging technique to diagnose and study Neuropathology of Neurological and Neuropsychiatric disorders.
Rajendra Badgaiyan, Professor, and Chairman at the Department of Psychiatry, Case Western Reserve University, and MetroHealth System, USA

Dr. Rajendra D. Badgaiyan, MD, is a psychiatrist and cognitive neuroscientist. He is Chairman of the Department of Psychiatry and Behavioral Sciences at Richmond University Medical Center, and Professor of Psychiatry at Icahn School of Medicine at Mount Sinai in New York. He received formal training in psychiatry, psychology, cognitive neuroscience, molecular imaging and neuroimaging. He was awarded the prestigious BK Anand National Research Prize in India and Solomon Award of Harvard Medical School. His research is focused on the study of neural and neurochemical mechanisms that control human brain functions. He developed the single scan dynamic molecular imaging technique (SDMIT) to detect, map, and measure neurotransmitters released acutely in the human brain during task performance. This technique is now used in laboratories all over the world. Using this technique, he studies dopaminergic control of human cognition and behavior. He is also interested in learning the nature of dysregulated dopamine neurotransmission in psychiatric and neuropsychiatric conditions. His research is funded by NIMH, NINDS, VA, and various foundations. Previously he served in the faculty of Harvard Medical School, SUNY Buffalo and University of Minnesota. He has published extensively in peer-reviewed journals.

Stress Conference 2024
Hall 1

Speaker Presentation

Title : Attention Aware Deep Learning Approaches for an Efficient Stress Classification Model.
Dr. Muhammad Zulqarnain, The Islamia University of Bahawalpur,  Pakistan

Dr. Muhammad Zulqarnain completed PhD degree at the age of 28 years from University Tun Hussein Onn Malaysia (UTHM), Johor, Malaysia in 2020. Currently, he is an Assistant Professor at the Faculty of Computer Science and Information Technology, The Islamia University of Bahawalpur (IUB), Pakistan. He has over 30 publications in national and international journals.  His research area includes artificial intelligence, deep neural networks, machine learning and natural language processing. He has approved PhD and master supervisor from Higher Education Commission of Pakistan. He acts as a reviewer for various journals and conferences, and has been served as a co-editor in a Springer conference proceeding. He presented papers in more than 15 national and international conferences.

Mental Health conference 2023
Hall 1

Poster Presentation

Title : Antipsychotic Metabolism as a Predictor of Treatment Response in Schizophrenia: Are Atypical Metabolisers More Likely to be Defined as Treatment Resistant?
Dr. Mia Pham, St Georges NHS Foundation Trust, UK

Dr. Mia Pham, a distinguished researcher at St. George’s NHS Foundation Trust, UK, is an authority in the realm of schizophrenia treatment. Her groundbreaking work centers on the interplay between antipsychotic metabolism and treatment outcomes, specifically focusing on the potential link between atypical metabolizers and treatment resistance in schizophrenia. With unwavering dedication, Dr. Pham explores the intricate nuances of this complex disorder, seeking to unravel the mysteries that shroud treatment response variability.

Neurology Conference 2024
Hall 1

Speaker Presentation

Title : Quality Control of Mitochondria in Parkinson’s disease (PD) Using ATP and Bradford Assays
Al-Baraa Akram El-Sayed, Department of Pharmaceutical Biotechnology, Portland Laboratory in De Montfort University in Leiceste, UK

Al-Baraa Akram El-Sayed is working as Research Assistant in De Montfort University in Department of Healthcare Science (Audiology)Leicester, United Kingdom. He published more than 15 research paper in last few year related to Parkinson’s disease

Neurology Congress 2024
Hall 1

Speaker Presentation

Title : Unlocking the Nexus of Neuroinflammation in the Olfactory Bulb association to Parkinson’s Disease
Dr. Aamer Mohammad, Rajiv Gandhi University of Health Sciences, USA
Fatma Rana Yilmaz, Nile University of Nigeria College of Health Science, Nigeria

Fatma Rana Yilmaz is currently pursuing her medical studies at the Nile University of Nigeria College of Health Science in Abuja, Nigeria. Her academic focus lies in the field of neuroscience, with a specialization in neuroinflammatory diseases and neurodegenerative diseases. She actively engages in research and analysis projects related to these areas.Aamer Mohammad holds a Doctor of Medicine degree from Rajiv Gandhi University of Health Sciences in India. He specializes in neuroscience, focusing on neuroinflammatory diseases and neurodegenerative diseases, as well as cardiovascular and stroke-related topics. Aamer has an impressive track record of research and analysis projects, with successful publications in renowned platforms such as the American Heart Association and the International Stroke Conference. His research on cannabis and its relationship with stroke has garnered significant media coverage, further highlighting his contributions to the field.”

Neurology congress 2024
Hall 1

Symposium

Title : Neuro-Cognitive Plasticity Therapy (NCPT)
Dr. Aakriti Varshney & Dr. Anand Pratap Singh, Gautam Buddha University, India

Aakriti Varshney is currently pursuing Ph.D. Psychology (Specialization in Clinical Neuropsychology, WP mode) from Deptt. of Psychology & Mental Health, Gautam Buddha University, Greater Noida. She is also working as a Consultant Clinical Psychologist at Shanti Home, KNEUS Hospital since September 2022. She has worked as assistant professor (on contract) at Department of Psychology and Mental Health, Gautam Buddha University since 2020 till 2022.Dr Anand Pratap Singh is currently working as Head, Department of Psychology & Mental Health, at Gautam Buddha University, India  since July, 2012.  Before joining the GBU, he has served at KGMU, Lucknow, Amity University, Noida, and Apollo Hospital Delhi in various capacities.  His area of expertise has been Brain fingerprinting, Neuro-Cognition and Neurofeedback Therapy. Till the date, he has supervised 08 Ph. D. theses and 29 M. Phil theses in the area of Clinical Neuro Psychology

Neurology Conference 2024
Hall 1

Oral Presentation

Title : Psychological and neuropsychological profile of patients with Parkinson’s disease undergoing DBS implantation: 8-year follow-up in a Rehabilitation Center
Herilckmans Belnis, Neuropsychologist at Sarah Network of Rehabilitation Hospitals, Brazil

Herilckmans Belnis is working as a neuropsychologist at Sarah Network of Rehabilitation Hospitals in Brazil. She attended many webinars and conferences in all over the world.

Neurology Conference 2024
Hall 1

Keynote Presentation

Title : Schizophrenia explained by a schizophrenic scientist
Anna Cornelia Beyer, Senior Lecturer- University of Hull, UK

She is an Eastern German (Berlin) born political science scholar (International Relations/ International Security) who worked at the University of Hull, UK, until 2019. Since 2002, she have a diagnosis of schizophrenia. she published 3 books about schizophrenia, which she believe is a spiritual illness.

Neurology Conference
Time: 09:45-10:10 Hall 1

Keynote Presentation

Title : Introduction to the principles of emotional processing and the effects of damage to the brain on emotional function.
Dr. Stephen E. Nadeau, University of Florida College of Medicine, USA

Dr. Nadeau studied chemical physics and political science at the Massachusetts Institute of Technology and achieved a medical degree at the University of Florida College of Medicine. After one year of post-MD fellowship training with Kenneth M. Heilman, he has devoted his research career mainly to cognitive neurology and, in particular, to understanding how higher neural functions can be supported by actual neurons. He is currently Professor of Neurology at the University of Florida. He has published two books and 158 peer-reviewed publications and book chapters.

Neurology Congress 2024
Hall 1

Poster Presentation

Title : Depression, Neuroplasticity and Generative Reprocessing Therapy (TRG): Case Report
Dr. Juliana Bezerra Lima-Verde, Brazilian Institute of Therapist Training (IBFT), Brazil

Juliana Bezerra Lima-Verde was a university professor and researcher in the field of Human Physiology and Neuroscience. She is certified in Reiki (Level II), kinesiology, transpersonal hypnotherapy, auriculotherapy, reflexology, and Generative Reprocessing Therapy (TRG), which she has been fully dedicated to since 2022. She currently serves as the scientific director of the Brazilian Institute of Therapist Training (IBFT), where she conducts research on TRG.

Neurology Congress 2024
Hall 1

Speaker Presentation

Title : An Investigation into the Synergistic Influence of Persistent Sinus Inflammation and onset dementia significance in the MCI subgroup, especially among male subjects.
Aamer Mohammad, Rajiv Gandhi University of Health Sciences, USAFatma Rana Yilmaz ,Nile University of Nigeria College of Health Science, Nigeria

Fatma Rana Yilmaz is currently pursuing her medical studies at the Nile University of Nigeria College of Health Science in Abuja, Nigeria. Her academic focus lies in the field of neuroscience, with a specialization in neuroinflammatory diseases and neurodegenerative diseases. She actively engages in research and analysis projects related to these areas.Aamer Mohammad holds a Doctor of Medicine degree from Rajiv Gandhi University of Health Sciences in India. He specializes in neuroscience, focusing on neuroinflammatory diseases and neurodegenerative diseases, as well as cardiovascular and stroke-related topics. Aamer has an impressive track record of research and analysis projects, with successful publications in renowned platforms such as the American Heart Association and the International Stroke Conference. His research on cannabis and its relationship with stroke has garnered significant media coverage, further highlighting his contributions to the field.”

Mayara Thais Moreira Neurology 2024
Hall 1

Speaker Presentation

Title : Investigation of Potential Molecular Markers in Treatment-Resistant Depression Through in Silico Approach.
Mayara Thais Moreira, Biotechnology Institute, Universidade de Caxias do Sul, Brasil.

Mayara Thais Moreira is working in  Biotechnology Institute at Universidade de Caxias do Sul, Brasil. She has published many research paper related to Artificial Intelligence (AI) in Diagnosis and Treatment.

2nd European Congress of Neurology and Neuropsychiatry
Hall 1

Speaker Presentation

Title : The Positive Dimension of Schizotypy is Associated with a Reduced Attenuation and Precision of Self generated Touch.
Evridiki Asimakidou, Karolinska Institutet, Stockholm, Sweden

Evridiki Asimakidou studied medicine at Aristotle University of Thessaloniki in Greece and graduated as the valedictorian in 2020. Afterwards, she moved to Sweden to continue with a master degree in Medical Research at Uppsala University. She spent the second year of her master studies in the USA and conducted her master thesis on glioblastoma immunotherapy at Northwestern University in Chicago. Starting from autumn 2023, she is currently a PhD student at Cambridge University, United Kingdom. During her PhD, she will investigate the immunological basis of Parkinson’s disease.

Mental Health conference 2023

Young Research Form Award Talks

YRF Presentation

Title : Role of EMG Biofeedback training on resting tremors and psychological well-being among patients with Parkinson’s disease
Vijeyata Chauhan, Gautam Buddha University, India

Vijeyata Chauhan is working in Gautam Buddha University, India. She want to abridge the gap between psychology and spirituality and like to answer some of the riddles of life and consciousness. Her aim at contributing towards the field of mental health also, which apparently has become a need of this era. Along with helping people overcome their mental health issues. She had an experience of dealing with patients suffering from various severe mental disorders.

Neurology Conference 2024

Poster Presentation

Poster Presentation

Title: Сognitive Impairment of Temporal Lobe Epilepsy and Some Risk Factors
Ulziizaya Sodov, National Mental Health Center, Mongolia.

She is one of the young aspiring doctors in Mongolia who is specialized at neurology. She have experience of working as a neurologist for 4 years and occupational health professional for 3 years. At the moment, She work at Intermed Hospital located in Ulaanbaatar, Mongolia as an occupational health physician and neurologist at the same time.

Neurology conference Russia

Young Research Form Award Talks

YRF Presentation

Title : No effect of motor synchronisation on oxytocin levels
Miss Elina Tsigeman, National University Higher School of Economics, Russia

Ms. Elina Tsigeman studied Psychology at the Tomsk State University, Russia and graduated as MSc in 2019. She worked at several universities in Russia and collaborated with international research teams from the UK and Germany to study personality, academic achievement and individual differences. In 2022, she joined the research group of Olessia Koltsova at the Laboratory for Social & Cognitive Informatics, National University Higher School of Economics, Saint-Petersburg, Russia.

Shubh Gulati, Gautam Buddha University, India

Young Research Form Award Talks

YRF Presentation

Title : Effectiveness of Computer-Assissted Virtual Cognitive Retraining in Patient with Learning Disability: A Case Study
Dr. Shubh Gulati, Gautam Buddha University, India

Ms. Shubh Gulati is pursuing her M.Phil. in Clinical Psychology (Batch:2021-2023) from Department of Psychology & Mental Health, Gautam Buddha University, Greater Noida, Uttar Pradesh, India. She has done various internships under clinical psychologist and psychiatrist and acquires an excellent skill in conducting psychodiagnostics assessments. She has presented her paper in an International Conference of Indian Academy of Health Psychology in 2022 in the area of Clinical Psychology. She has received a token of appreciation as conference coordinator at during 7th International Conference of Indian Academy of Health Psychology (7th-ICIAHP). Her area of expertise has been psychotherapy, psychodiagnostics assessments and counseling techniques.

Neurology Conference

Young Research Form Award Talks

YRF Presentation

Title : Effectiveness of Neurofeedback Therapy on P300 Event Related Potential and Neurocognitive Functioning among Schizophrenic patients.
Dr. Aakriti Varshney, Gautam Buddha University, India

Ms. Aakriti Varshney is currently pursuing Ph.D. Psychology (Specialization in Clinical Neuropsychology) from Deptt. of Psychology & Mental Health, Gautam Buddha University, Greater Noida. Her area of expertise has been Neuro-Cognition, Neurofeedback Therapy, Neural Entrainment Therapy and Brain Fingerprinting Technique. She has published various research papers and book chapters in the area of neurofeedback therapy and clinical psychology. She has participated in various International and national conferences, workshops and seminars. She has also published a patent on the topic: Method and System for Investigating Psychopathology with Brain Fingerprinting Technique (BFT).

European Congress of Neurology

Young Research Form Award Talks

YRF Presentation

Title : Effectiveness of Computer-Assisted Cognitive Retraining among Patients with Mild Cognitive Impairment: A Comparative Study
Ms. Somya Singh, Gautam Buddha University, India

Somya Singh completed her Master of Arts in Clinical Psychology from Lucknow University in 2018. She furthered her studies with an M.Phil in Clinical Psychology from Gautam Buddha University, Greater Noida, in 2023. During her M.Phil, she underwent clinical training at various Psychiatry departments.

Neurology Congress 2024

Young Research Form Award Talks

YRF Presentation

Title : Effectiveness of Cognitive Retraining on Executive Function among Patients with Schizophrenia.
Pragya Singh, Department of Psychology & Mental Health, India

Ms. Pragya Singh is pursuing her M.Phil. in Clinical Psychology (Batch:2021-2023) from Department of Psychology & Mental Health, Gautam Buddha University, Greater Noida, Uttar Pradesh, India. She has done various internships under clinical psychologist and psychiatrist and acquires an excellent skill in conducting psychodiagnostics assessments. She has presented her paper in an International Conference of Indian Academy of Health Psychology in 2022 in the area of Clinical Psychology. She has received a token of appreciation as conference coordinator at during 7th International Conference of Indian Academy of Health Psychology (7th-ICIAHP). Her area of expertise has been psychotherapy, psychodiagnostics assessments and counseling techniques

Neurology Congress 2024
Hall 1

Speaker Presentation

Title : An Investigation into the Synergistic Influence of Persistent Sinus Inflammation and onset dementia significance in the MCI subgroup, especially among male subjects.
Aamer Mohammad, Rajiv Gandhi University of Health Sciences, USAFatma Rana Yilmaz ,Nile University of Nigeria College of Health Science, Nigeria

Fatma Rana Yilmaz is currently pursuing her medical studies at the Nile University of Nigeria College of Health Science in Abuja, Nigeria. Her academic focus lies in the field of neuroscience, with a specialization in neuroinflammatory diseases and neurodegenerative diseases. She actively engages in research and analysis projects related to these areas.Aamer Mohammad holds a Doctor of Medicine degree from Rajiv Gandhi University of Health Sciences in India. He specializes in neuroscience, focusing on neuroinflammatory diseases and neurodegenerative diseases, as well as cardiovascular and stroke-related topics. Aamer has an impressive track record of research and analysis projects, with successful publications in renowned platforms such as the American Heart Association and the International Stroke Conference. His research on cannabis and its relationship with stroke has garnered significant media coverage, further highlighting his contributions to the field.”

Poster Session Day 1

Time: 11:00- 15:00 (Hall 1)

Professor Masaki Kakeyama, Director of Research Institute of Environmental Medical Sciences

Poster 1

Poster Presentation

Title : Cognitive flexibility in experimental animals as an index of cognitive decline of AD.

Masaki Kakeyama, Laboratory for Environmental Brain Science, Waseda University Faculty of Human Sciences, Japan

Dr. Kakeyama studied Neuroscience at Waseda University and received Ph.D. in 1995. Researcher at National Institute for Environmental Studies, Japan for 8 years, assistant professor at Tokyo University for 8 years, and in present, professor of Waseda University Fucluty of Human Sciences. Paper Count: 70, Citation Count:2891.

Abstract:

Cognitive flexibility is the ability of adapting to an ever-changing environment, and is demonstrated by making full use of memory, experience and knowledge with paying close attention to ever-changed environment. It declines with aging and impaired in early stages of dementia. However, traditional animal experiments, even in dementia study, have focused on simple memory tasks that involve remembering and recalling inorganic conditions, whereas rodents can also shows extremely good cognitive performance by using its own prior knowledge. We have developed multiple behavioral test methods using touch-screen operant apparatus and IntelliCage apparatus. A common feature of the two analysis systems is that experimental animals are rewarded by showing the correct behavioral sequence based on spatial cues, and the difference is that touchscreen apparatus requires a very small distance to move, while IntelliCage apparatus requires a distance of several hundred steps. By using these systems, we have found that probiotic treatment with a mixture of Bifidobacterium animalis subsp. lactis LKM512 and arginine improved cognitive flexibility in young and middle aged mice, indicating probiotic treatment might contribute prevention and delay of onset of dementia. Alzheimer’s model, APP knock-in mice were found to be inhibited performance of cognitive flexibility even at the aging stage when they showed identical performance of memory score with control mice. These results strongly suggest the importance of cognitive flexibility as an index of dementia.

Keywords: cognitive flexibility, mental schema, Alzheimer’s disease

Acknowledgements: This works is supported in part by Grant-in-Aid for Scientific Research from Japan Society for the Promotion of Science (19H01152, 20H00575, and 23H00522 to M.K.), Brain Mapping by Integrated Neurotechnologies for Disease Studies (Brain/MINDS) Grant from Japan Agency for Medical Research and Development (JP19dm0207079h to M.K.).

Video Presentation:

Title : Harnessing Artificial Intelligence/Machine Learning in Rare Diseases: Living with Arachnoiditis – An International Study by ACMCRN.
Lori Verton, Arachnoiditis & Chronic Meningitis Collaborative Research Network (ACMCRN), Canada

Lori Verton BSc RCPT graduated from Western University in Ontario Canada in 1988. She worked from that time until 2000 as a Registered Cardiopulmonary Technologist. She began working as a Clinical Research Associate in Respirology at Queens University in Canada from 2001 to 2010 before retiring due to disability caused by Arachnoiditis. Since 2016 she has completed a number of rare disease leadership and development certificates, including rare disease leadership training and research development courses from EURODIS, Beacon Findacure and others. In 2017,

Lori co-founded ACMCRN with 2 others in the Arachnoiditis community. Its vision is to better the lives of those with Arachnoiditis. Its mission is to provide peer support, patient and provider educational materials and to lead an international research program, inviting global Arachnoiditis researchers to work together in a collaborative effort to advance quality research into the condition.

Lori has previous experience as a Director and entrepreneur including as a Director of a Community Health Center board, and as a member of a municipal committee on Disability and Inclusion. She has owned a small media and publishing company

Yousef HAWAS, Neurology Congress 2024

Poster 2

Poster Presentation

Title :TRANSCRANIAL DIRECT CURRENT STIMULATION (TDCS) IN TREATMENT OF REFRACTORY EPILEPSY: A SYSTEMATIC REVIEW AND META-ANALYSIS

Yousef Hawas, Faculty of Medicine, Tanta University, Gharbeya, Egypt

Mr. Yousef is an MBBCh candidate at the Faculty of Medicine, Tanta University, Egypt. He joined the medical research group of Prof. Ahmed Negida in Massachusetts, USA. He is an official member at the American Academy of Neurology and the European Academy of Neurology. He has published 3 articles this year and more than 15 manuscripts are still under the peer-review process.

Abstract:

Introduction

Around 30% – 40% of patients with epilepsy continue to experience seizures despite the currently available treatments [1]. Transcranial direct current stimulation (tDCS) has emerged as a promising non-invasive neuromodulation approach for treating refractory epilepsy. This study aims to provide a comprehensive examination of the safety and efficacy of tDCS in patients with refractory epilepsy.

Material and Methods

Following the PRISMA guidelines, PubMed, Ovid MEDLINE, Embase, EBSCO, Scopus, Cochrane Central, and WOS (Web of Science) were searched from inception until June 2023 to identify relevant RCTs. Search results were compiled in Rayyan [2]. Data were extracted and analyzed with RevMan web software [3]. Variables such as electrodes location, current intensity, number of sessions, duration of stimulation, frequency and duration of epilepsy, and complications were extracted. Pooled mean difference was calculated for change in seizure frequency (SF), and number of Interictal epileptiform discharge (IED) at four and eight weeks. Cochrane ROB-II was used to assess the quality of the included studies.

Results and Discussion:

We included 8 RCTs with a total of 242 patients. Compared to the sham group, tDCS patients had a significantly lower seizure frequency at four and eight weeks of follow-up (MD= -4.72, 95% CI [-6.80, -2.65] P < 0.05) and (MD = -3.39, 95% CI  [-6.07, -0.72], P < 0.05), respectively. The IED was observed to decline at 4 weeks of follow-up (MD = -5.35, 95% CI  [-7.70, -2.99], P < 0.05). The reported adverse events were not serious. It includes only mild itching and erythematous rash that resolved spontaneously.

Conclusion

It was found that tDCS significantly reduced SF and the number of IED. However, there was heterogeneity in the SF at eight weeks of follow-up. Future large RCTs with a standard clear informed stimulation protocol are needed further to promote tDCS therapy in the management of refractory epilepsy.

Keywords: Refractory Epilepsy, Transcranial Direct Current Stimulation, tDCS, Quantitative synthesis